Ellen Greene was performing as a nightclub singer in several New York City clubs and treading the boards in New York City theater before her friend and mentor, filmmaker
Paul Mazursky cast her in her first motion picture,
Next Stop, Greenwich Village (1976), she was awarded the part of Sarah, opposite
Lenny Baker. Four years after she originated the role of Audrey, the lovably ditzy, golden-hearted, sweetest masochist in musical-comedy history in
Howard Ashman's 1982 Off-Broadway play, The Little Shop of Horrors, the actress reprised the role in
Frank Oz's film adaptation,
Little Shop of Horrors (1986) (in which she starred opposite
Rick Moranis and
Steve Martin). Up to the present time, this is the actress's most talked-about and celebrated role.
A few years later, Greene starred in the American drama film
Talk Radio (1988), she played the part of Ellen, opposite
Eric Bogosian and
Alec Baldwin. Aside from the actress's work in these two motion pictures, and ABC's fantasy mystery comedy-drama television series,
Pushing Daisies (2007), in which she and
Swoosie Kurtz play Lily and Vivian Charles, the agoraphobic sisters. Greene has also provided her talent to
Law & Order (1990),
The X-Files (1993),
Heroes (2006), and
The Young and the Restless (1973).
In July 2015, Greene brought back Audrey for a two-night revival of Little Shop of Horrors at New York City Center. She starred opposite
Jake Gyllenhaal (who replaced Moranis). The revival received rave reviews, and according to The New York Times, when Greene made her entrance on stage, she received the kind of entrance applause you might imagine greeting the resurrection of
Maria Callas at the Metropolitan Opera for a beyond-the-grave performance of "Norma."