She was born in Madrid in a family of actors, the daughter of the actor Adolfo Marsillach and the actress and model María Teresa del Río Martínez del Cerro, who was also Miss Spain, 1960. Her sister Blanca is also an actress.
She took piano, body expression and ceramics classes. She began to enter the world of cinema at the age of thirteen, with a small role in "Mrs. Garcia Confesses". Later, she was making some short films, where she worked as a script and lighting technician. Her first important film was in "El Poderoso Influjo de la Luna", "Crime in the Family", "The Sea and Time", and "Last Days with Teresa". She also appeared in such television shows as "High School" and the second season of "Chronicle of the Sunrise".
She is the artistic director of the Marsillach Acting Academy in Madrid, Spain.
Her best known film is 1986's Every Time We Say Goodbye, in which she starred opposite Tom Hanks.
Simple Like Silver(2021)as Lucia
Schwarz greift ein(1994)as Rita Blum
Un posto freddo in fondo al cuore(1992)
Barocco(1991)as Valeria
L'amour maudit de Leisenbohg(1991)as Fanny
Dario Argento: Panico(2023)as Self
Furor(1998)as Self - Contestant
Juego de niños(1988)as Self - Contestant
Dario Argento: Master of Horror(1991)as Self
Ochéntame... otra vez(2014)as Self
La tele de tu vida(2007)as Isabel
